Telepathology is the electronic transmission of computerized or digital images that can be utilized for diagnostic consultation. The system comprises of a microscope with a mounted digital camera linked to a computer. The pathologist selects the video images for analysis and then submits a diagnostic report.

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Telepathology systems are divided into three major types: static image-based systems, real-time systems, and virtual slide systems. Static image systems have significant advantages of being the most sensibly valued and are usable in most settings; however the downside is that just the chosen subset of microscopic fields are transmitted for review by the pathologist. Real-time systems and virtual slides permit a specialist pathologist the chance to evaluate the entire specimen. With real-time systems, the specialist effectively works a microscope located at a distant site – changing focus, illumination, magnification, and field of view at will. Virtual slide systems use a robotized scanner that takes a visual image of the whole slide, which can then be sent to another area for diagnosis.